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IPEN Body Burden Community Monitoring Handbook PesticidesCHLORDANE Chemical Name: 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene (C10H6Cl8). CAS Number: 57-74-9 Properties: Solubility in water: 56 µg/L at 25°C; vapour pressure: 0.98 x 10 -5 mm Hg at 25 °C; log KOW: 6.00. Discovery/Uses: Chlordane appeared in 1945 and was used primarily as an insecticide for control of cockroaches, ants, termites, and other household pests. Technical chlordane is a mixture of at least 120 compounds. Of these, 60-75% are chlordane isomers, the remainder being related to endo-compounds including heptachlor, nonachlor, diels-alder adduct of cyclopentadiene and penta/hexa/octachlorocyclopentadienes. Persistence/Fate: Chlordane is highly persistent in soils with a half-life of about 4 years. Its persistence and high partition coefficient promotes binding to aquatic sediments and bioconcentration in organisms. Toxicity: LC50 from 0.4 mg/L (pink shrimp) to 90 mg/L (rainbow trout) have been reported for aquatic organisms. The acute toxicity for mammals is moderate with an LD50 in rat of 200-590 mg/kg body weight (19.1 mg/kg body weight for oxychlordane). The maximum residue limits for chlordane in food are, according to FAO/WHO between 0.002 mg/kg milk fat and 0.5 mg/kg poultry fat. Water quality criteria of 1.5 to 6 µg/L have been published. Chlordane has been classified as a substance for which there is evidence of endocrine disruption in an intact organism and possible carcinogenicity to humans. Source: UNEP Chemicals, Regional Reports of the Regionally Based Assessment of Persistent Toxic Substances Program (2002) Available from: http://www.chem.unep.ch/pts UNEP Chemicals 11-13, chemin des Anemones CH-1219 Chatelaine, GE Switzerland. 
IPEN Body Burden Community Monitoring Handbook - 2003 |
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