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IPEN Body Burden Community Monitoring Handbook PesticidesENDRIN Chemical Name: 3,4,5,6,9,9-Hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphth[2,3-b]oxirene (C12H8Cl6O). CAS Number: 72-20-8 Properties: Solubility in water: 220-260 µg/L at 25 °C; vapour pressure: 7 x 10 -7 mm Hg at 25°C; log KOW: 3.21-5.34 Discovery/Uses: It has been used since the 50s against a wide range of agricultural pests, mostly on cotton but also on rice, sugar cane, maize and other crops. It has also been used as a rodenticide. Persistence/Fate: Is highly persistent in soils (half-lives of up to 12 years have been reported in some cases). Bioconcentration factors of 14 to 18,000 have been recorded in fish, after continuous exposure. Toxicity: Endrin is very toxic to fish, aquatic invertebrates and phytoplankton; the LC50 values are mostly less than 1 µg/L. The acute toxicity is high in laboratory animals, with LD50 values of 3-43 mg/kg, and a dermal LD50 of 5-20 mg/kg in rats. Long term toxicity in the rat has been studied over two years and a NOEL of 0.05 mg/kg bw/day was found. Source: UNEP Chemicals, Regional Reports of the Regionally Based Assessment of Persistent Toxic Substances Program (2002) Available from: http://www.chem.unep.ch/pts UNEP Chemicals 11-13, chemin des Anemones CH-1219 Chatelaine, GE Switzerland. 
IPEN Body Burden Community Monitoring Handbook - 2003 |
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